Durvalumab with cisplatin and etoposide
WebDurvalumab is approved to treat adults with: Biliary tract cancer, including cholangiocarcinoma and gallbladder cancer, that has spread. It is used with gemcitabine hydrochloride and cisplatin. Hepatocellular carcinoma (a type of liver cancer) that cannot be removed by surgery. It is used with tremelimumab-actl. Non-small cell lung cancer … WebApr 16, 2024 · In terms of trial CASPIAN, patients were assigned to receive durvalumab plus etoposide-cisplatin (EP) or etoposide-carboplatin (EC) regimen. Patients received up to 4 cycles of chemotherapy plus durvalumab 1500 mg followed by maintenance durvalumab 1500 mg every 4 weeks or placebo. [7]
Durvalumab with cisplatin and etoposide
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WebDec 5, 2024 · Rudin CM, Awad MM, Navarro A, et al. Pembrolizumab or Placebo Plus Etoposide and Platinum as First-Line Therapy for Extensive-Stage Small-Cell Lung … WebApr 16, 2024 · In terms of trial CASPIAN, patients were assigned to receive durvalumab plus etoposide-cisplatin (EP) or etoposide-carboplatin (EC) regimen. Patients received …
WebThe patient underwent one cycle of induction chemotherapy with cisplatin and etoposide. Positron-emission tomography/computed tomography (PET-CT) after induction chemotherapy showed the tumor increased in size. The patient received volumetric modulated arc therapy (VMAT) with simultaneous integrated boost (SIB) and the … WebDurvalumab (IMFINZI ®) + etoposide with either cisplatin or carboplatin is a Category 1, preferred treatment option for first-line ES-SCLC 3‡§ ES-SCLC=extensive-stage small cell lung cancer; EP=etoposide and either …
WebFeb 6, 2024 · Patients were randomized in a 1:1:1 ratio to receive treatment with durvalumab + tremelimumab + etoposide and platinum-based chemotherapy (EP), durvalumab + EP or EP alone. 987 participants were randomized in the study overall. ... (80-100 mg/m^2) with either carboplatin (area under the curve 5-6) or cisplatin (75-80 … WebAug 25, 2024 · Carboplatin area under the curve 5–6 mg/mL per minute or cisplatin 75–80 mg/m 2, administered on day 1 of each cycle. Durvalumab 1,500 mg every 3 weeks …
WebApr 11, 2024 · Two phase 3 trials evaluated the addition of programmed cell death-ligand 1 (PD-L1) inhibitor atezolizumab (IMpower133) (5, 6) or durvalumab (CASPIAN) (7, 8) to first-line chemotherapy (etoposide and cisplatin [EP]) followed by maintenance PD-L1 inhibitor in patients with ES-SCLC, and showed a significant improvement in overall survival (OS ...
WebDec 4, 2024 · First-line durvalumab plus etoposide with either cisplatin or carboplatin (platinum–etoposide) showed a significant improvement in overall survival versus … early voting in ncWebA Phase III, Randomized, Open-Label, Multi-Center, Global Study to Determine the Efficacy and Safety of Durvalumab in Combination With Gemcitabine+Cisplatin for Neoadjuvant Treatment Followed by Durvalumab Alone for Adjuvant Treatment in Patients With Muscle-Invasive Bladder Cancer early voting in newport riWebFeb 28, 2024 · The EP regimen (etoposide plus cisplatin), in particular, ... CASPIAN, aimed to explore the efficacy of the anti–PD-L1 antibody durvalumab and the anti–CTLA … early voting in newburgh indianaWebApr 11, 2024 · Two phase 3 trials evaluated the addition of programmed cell death-ligand 1 (PD-L1) inhibitor atezolizumab (IMpower133) (5, 6) or durvalumab (CASPIAN) (7, 8) to … csumb myhousingWebA Phase III, Randomized, Open-Label, Multi-Center, Global Study to Determine the Efficacy and Safety of Durvalumab in Combination With Gemcitabine+Cisplatin for Neoadjuvant … early voting in nc datesWebAug 24, 2024 · Imfinzi is approved for first-line use in combination with etoposide and either carboplatin or cisplatin. Administration Imfinzi is given by intravenous infusion over approximately 60 minutes. early voting in newton countyWebThe National Library of Medicine (NLM), on the NIH campus in Bethesda, Maryland, is the world's largest biomedical library and the developer of electronic information services that delivers data to millions of scientists, health professionals and members of the public around the globe, every day. early voting in new braunfels tx